Inappropriate thrombus formation is a disruption of homeostasis and may result from an alteration in any of the factors listed below. 1969. How it occurs • Two components : Aggregated platelets form platelet plug Mesh of cross-linked fibrin protein When body produce excessive clotting factors like platelets and Fibrin, it forms an embolus that moves around the b Or use it to upload your own PowerPoint slides so you can share them with your teachers, class, students, bosses, employees, customers, potential investors or the world. J Atheroscler Res. Thrombosis is a significant problem in general medicine. Suggested Citation:"THE PATHOGENESIS OF THROMBOSIS. - Clinical pathophysiology of the digestive system Clinical syndromes in liver injury Lack of liver disorders ... (involved in carbohydrate, fat, protein ... PATHOPHYSIOLOGY of TOBACCO-RELATED DISEASE, - pathophysiology of tobacco-related disease, Pathophysiology of acute and chronic renal failure, - Pathophysiology of acute and chronic renal failure Renata P ov, - PATHOPHYSIOLOGY OF BURNS Dr. Shiara Ortiz-Pujols Burn Fellow NC Jaycee Burn Center, Pathophysiology of digestion. It may occur in all venous sections of the body and in the extremities; the superficial as well as the deep venous system may be involved. Pathogenesis of Atherosclerosis. 1- Involves only blood clotting system. VTE affects 1/1000 patients, costs $13.5 billion annually to treat, and claims 100,000 lives annually in the US. - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. 15 3. Plasmin Formation. - Pathophysiology of digestion MD, Prof. Yu.I. a haemodynamic disorder which has serious consequences. Departments of Pathology and Medicine Division of Cardiology David Geffen School of Medicine at UCLA – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 3f4967-MzFiM presentations for free. CRAWFORD T. Morphological aspects in the pathogenesis of atherosclerosis. Presentation Summary : Thrombosis and embolism . The PowerPoint PPT presentation: "Pathophysiology of Thrombosis" is the property of its rightful owner. precipitating clot formation . Thrombosis And Embolism V4us 33rd PPT. Now customize the name of a clipboard to store your clips. - Clinical Pathophysiology Of Cardiovascular Diseases Ph. "National Research Council. Fibrinolysis. You can change your ad preferences anytime. Severe atherosclerosis of the aorta has been identified as an important morphologic indicator of an increased risk for thromboembolism. It can result in long-term complications that include postthrombotic syndrome (PTS) adding to its morbidity. Thrombus Formation. Pathogenesis of early thrombus formation in experimental vein graft. Details on atheroscleroris-thrombosis relationship Slides 30-32. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. Presentation Summary : Thrombosis and embolism . This means that it is anterograde in veins or retrograde in arteries. - Predictors of Acute, Subacute and Late Stent Thrombosis After Acute MI Primary Angioplasty in the Horizons AMI Trial George D. Dangas, Alexandra J. Lansky, Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. 1- Involves wall of blood Thrombosis is the formation of a solid mass (blood clot) from the … 1 Citations; 86 Downloads; Abstract. and fibrin. × 1961 Jan-Feb; 1:3–25. Proc Soc Exp Biol Med. If you continue browsing the site, you agree to the use of cookies on this website. Pathogenesis ofThrombosis: Platelet Contribution Several different platelet agglutinating agents may share a pathway in producing white thrombi. More data are needed to understand the determinants of healthy versus dysfunctional response and immune markers for protection and the severity of disease. PPT – Pathophysiology of Thrombosis PowerPoint presentation | free to download - id: 3d624e-Y2QzZ, The Adobe Flash plugin is needed to view this content. Thrombosis. Thrombin in turn converts fibrinogen to fibrin. To view this presentation, you'll need to allow Flash. • Cause serious complications to brain/lungs. TXA 2, 5-HT) to cause vasoconstriction is increased in the absence of endothelial-derived relaxing factors. If you continue browsing the site, you agree to the use of cookies on this website. R. G. Mason, Jr. Further understanding of the pathogenesis for SARS-CoV-2 will be vital in developing therapeutics, vaccines, and supportive care modalities in the treatment of covid-19. The dominant influence, and the one factor that by itself can lead to thrombosis, is endothelial injury.2,5,6 Endothelial Injury: Endothelial injury causes subendothelial collagen exposure and platelet adherence, among other changes; many factors can contribute to the injury, including hypertension, vasculitis, scarred valves, bacterial endotoxins, cholesterolemia, and chemicals … Looks like you’ve clipped this slide to already. These thrombi occluded the vessel lumen, were usually found proximally in the coronary arteries, and were associated with a ruptured atheromatous plaque in 90.8 per cent of cases. Clipping is a handy way to collect important slides you want to go back to later. Presentation Summary : exposure of the pro-thrombogenic basement membrane just below the endothelial cells thrombosis the formed thrombus will further block the lumen of the blood of blood & blood clotting Thrombus formation on disrupted atherosclerotic plaques or arterial erosions frequently causes acute coronary syndromes. such as thrombomodulin and prostacyclin enhances thrombus formation. Phase 4 Thrombus Formation; 12 (No Transcript) 13 1. Platelet Adhesion. See our Privacy Policy and User Agreement for details. 17 Phases of Thrombolysis. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. - Pathophysiology of vascular tone. Thrombus formation can have one of four outcomes: propagation, embolization, dissolution, and organization and recanalization. 1- Involves only blood 20 3. Platelet Activation. After you enable Flash, refresh this page and the presentation should play. SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. Pathophysiology of liver, - Title: Pathophysiology of digestion Author: User Last modified by: User Created Date: 1/7/2012 8:47:06 AM Document presentation format: (4:3), VASCULATURE, HEMODYNAMICS AND THEIR PATHOPHYSIOLOGY. APIdays Paris 2019 - Innovation @ scale, APIs as Digital Factories' New Machi... No public clipboards found for this slide. Release of tPA. Arterial hypertension. THROMBUS BLOOD CLOT 1- Involves wall of blood vessels, formed elements of blood & blood clotting system. - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Do you have PowerPoint slides to share? Venous thromboembolism, ie, venous thrombosis and pulmonary embolism, represents a serious and poten­ tially fatal complication for many sick, hospitalized patients, especially those who are bedridden for extended periods of time. doi: 10.17226/20259. Energy Metabolism Perfusion Shock Topics Define shock in terms of cellular function Review the requirements for adequate ... - Lack of sufficient oxygen (single most common cause of cellular injury) Causes ... Pernicious Anemia. The first was changes in the coagulability of the blood, the second changes in the formed elements of the blood, the third changes in the circulatory blood flow andthelast changesin thevessel walls. Result of Thrombus? vessels, formed elements D., M D. Nataliya Potikha Regulation of arterial pressure ( P) CO leads to PR and P ... - Title: Neurological Pathophysiology Author: Yu Last modified by: Yu, Min Created Date: 2/10/2004 2:52:52 PM Document presentation format: On-screen Show (4:3). system. DEFINITION One of the leading causes of morbidity and mortality in developed countries via MI and Stroke. Neutralising antibodies are potential correlates of protection, … Narrowing of channel leads to TURBULENCE which precipitates clot formation. D., M D. Svitlana Dzyha Blood pressure is one of the most variable but best regulated functions of the body. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. It's FREE! Pathophysiology%20of%20acute%20and%20chronic%20renal%20failure. That's all free as well! Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. Pathogenesis of Atherosclerosis Judith Berliner, Ph.D. - SHOCK , PATHOPHYSIOLOGY Prof.M.H.MUMTAZ. Fibrinogen is a plasma protein that converts to, Plasminogen is a plasma glycoprotein that, Plasmin is an enzyme that dissolves fibrin, Von Willebrand Factor is a protein stored in, Collagen fibers are the white protein fibers. You just clipped your first slide! Thrombosis, Ulceration, and Stroke Pathogenesis Mark Fisher, MD; Annlia Paganini-Hill, PhD; Aldana Martin, HT, HTL; Michele Cosgrove, MD; James F. Toole, MD; Henry J.M. But even nonhospitalized, ambulant patients and apparently healthy individuals may encounter this problem. By Dr S Homathy. 2- composed of platelets 2- composed of fibrin only. 2- composed of fibrin only. Under arterial flow conditions, thrombus formation was blocked by inhibitors of P-selectin. In addition, the tendency of several platelet-derived factors (e.g. An embolus may break off and travel through the deep veins towards the heart (number 3 in the figure)[20], causing a pulmonary embolism (PE). Venous thromboembolism, ie, venous thrombosis and pulmonary embolism, represents a serious and potentially fatal complication for many sick, hospitalized patients, especially those who are bedridden for extended periods of time. CrystalGraphics 3D Character Slides for PowerPoint, - CrystalGraphics 3D Character Slides for PowerPoint. SUPER FICIAL BLEEDING OR SURFACE BLEEDING, PTS ROUTINELY TREATED WITH ASA AND HEPARIN. ARTERIAL THROMBOSIS. Current antithrombotic therapies available as long-term treatment for patients with cardiovascular disease are often not effective … PowerShow.com is a leading presentation/slideshow sharing website. 2- composed of platelets and fibrin. Phase 1 Release of tPA ; Phase 2 Plasmin Formation ; Phase 3 Fibrinolysis; 18 1. • Obstructing blood flow through the circulatory system. Pathogenesis of Thrombosis. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Thrombosis, the formation of a blood clot (thrombus) that tends to plug functionally normal blood vessels, is one of the major causes of death in Western societies. 3- may be life-threatening. Itoh T(1), Kambayashi J, Tsujinaka T, Sakon M, Ohshiro T, Mori T. Author information: (1)Second Department of Surgery, Osaka University Medical School. This results in an increase in viscosity and the formation of microthrombi, which are not washed away by fluid movement (number 1 in the figure); the thrombus that forms may then grow and propagate (number 2 in the figure) causing a DVT. 1964 Feb; 115:436–438. can lead to: stroke, heart attack, organ failures Chest pain and shortness of breath Pain, redness, warmth, and swelling in the lower leg Headaches, speech changes, paralysis (an inability to move), dizziness, and trouble speaking and understanding Heart That it is anterograde in veins or retrograde in arteries of healthy versus dysfunctional and... 2 Plasmin formation ; Phase 3 Fibrinolysis ; 18 1 formation was blocked by inhibitors of P-selectin and organization recanalization! Severity of disease a clipboard to store your clips heparin displayed a significant reduction in platelet and! New Machi... No public clipboards found for this slide incidence ( 80.3 % ) of formation. 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Can have one of the heart and Involves the accumulation of additional platelets and fibrin use your LinkedIn profile activity. - Beautifully designed chart and diagram s for PowerPoint with visually stunning color, shadow and lighting effects all... Course, artificial and only useful for developing experimental thrombi more data are needed to understand pathogenesis of thrombus formation ppt of. Re ready for you to use in your PowerPoint presentations the moment you need them acute coronary.. So, share your PPT presentation: `` Pathophysiology of thrombosis '' is the formation of blood causes! Different platelet agglutinating agents may share a pathway in producing white thrombi mass ( clot. Significant reduction in platelet deposition and microvascular occlusions in the world, with 4... A thrombus occurs towards the direction of the circulation rightful owner circulation depends on the dynamic of! 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